GLP-1s in MS: New CMSC data in Charlotte found GLP-1 receptor drugs were linked to more physical activity and better patient-reported symptom scores in people with multiple sclerosis. Biotech pipeline: Dyne Therapeutics filed a biologics license application for zeleciment rostudirsen (z-rostudirsen) for Duchenne muscular dystrophy, seeking accelerated FDA approval. Local business: Triangle company Grow Fragrance is selling plant-based candles and home scents made with plant wax and fragrances instead of petroleum-derived ingredients. Rural health funding: Rep. Don Davis highlighted $3.36 million in federal support for Rural Health Group in Roanoke Rapids, plus funding for five other eastern NC community health centers. Small business growth: A CoworkingCafe study ranked the Raleigh-Cary metro No. 4 for small business performance, citing strong formation and tech talent. Transit vs growth: A new analysis argues North Carolina’s denser cities won’t automatically boost public transit ridership, with many residents still preferring cars, walking, or remote work. Major project: Buc-ee’s is set to break ground June 10 in Mebane, with an opening targeted for late 2027. Public safety: A deadly I-95 bus crash in Virginia killed five and injured dozens; federal investigators are looking at driver licensing and safety oversight.